With the modularity of our design, obtaining higher field strength systems from Bruker Daltonics can be done on initial order or as a magnet retrofit to existing systems on site. Capabilities such as FTMS dynamic range, center of mass collision energy and ion storage capacity show quadratic enhancement with field. Performance, Versatility, Confidence: Many important analytical properties increase with the square of magnetic field strength. In addition extended performance versions of apex-Qe are available at 9.4 Tesla and now 12 Tesla – the worlds highest commercially available FTMS field strength. Magnet Choices: Bruker Daltonics offers ultra high performance actively shielded magnet technology with 7 Tesla on the standard apex-Qe system. Wide m/z range simultaneous detection of ions (e.g. Qh-hybrid along with CID and ECD for “top-down” proteomics (Top↓Pro™) facilitates selected gas phase ion enrichmentĮxtreme resolution capability for direct analysis of complex mixtures (> 600,000 FWHM) Automated software to confirm composition with m/z and isotopic pattern informationĮxact mass MS(n) capability for detailed structural analysis and peptide sequencing LC/MS/MS with data dependent acquisition using Bruker’s simple, unified Compass software packageĮxact mass MS analysis to sub-ppm levels for unambiguous determination of elemental chemical composition. The combined power of the new hybrid configuration features:

Merging the latest quadrupole technology (complete with linear ion trapping modes), a superb multipole collision cell, together with the highest performing FTMS available is a quantum leap in capability. With the APEX-Q, the life science researcher now has access to automated data dependent MS/MS functionality operating with dynamic exclusion lists, inclusion lists and other 'smart' MS/MS proteomics protocols with the added benefit of FTMS caliber performance. The new high-field APEX-Q can deliver sub-ppm mass accuracy, enormous resolving power for peptide mixtures, wide bandwidth detection, high dynamic range, and fast automated data-dependent MS/MS for detailed proteome characterization when coupled on-line to liquid chromatography. This novel combination further increases the superb resolution and mass accuracy of FTMS by using the latest proprietary high-field magnet technology, while adding facile and efficient precursor mass selection and collision induced dissociation in a conventional Qh 'front end' for on-the-fly data-dependent MS/FTMS fragmentation, or selected accumulation of LC-separated protein digests.Ĭombining online femtomole sensitivity with ppm mass accuracy on LC-MS and LC-MS/MS data gives the specificity for even the most complex ID and de novo applications.

Bruker apex software